Disputation von Konrad Diedrich am 04.04.2025, 15:00 Uhr

4. April 2025, von Reinhard Zierke

Einladung zur hochschulöffentlichen Disputation im Rahmen des Promotionsverfahrens von Konrad Diedrich

Titel der Dissertation: Development of a web-based system for geometric mining in protein structure collections

Proteins and their intermolecular interactions with ligands are essential for controlling the development, capabilities, and health of organisms. Consequently, computer-aided drug design aims to support the analysis of proteins and protein-ligand complexes stored in databases like the Protein Data Bank. Two methods, accessible as web-based applications, were developed in this doctoral project to meet the demand for analysis tools. The first tool generates interactively customizable 2D visualizations of ligand binding modes. The second tool enables geometric searches in binding sites of the Protein Data Bank through a comprehensive interface design. Together, they built a perfect framework for mining protein-ligand binding sites.

Datum und Uhrzeit: Freitag, 4. April 2025 um 15:00 Uhr
Ort: Albert-Einstein-Ring 8-10, Raum 0005/0010
Betreuer: Prof. Dr. Matthias Rarey

Prof. Dr. Matthias Rarey
Vorsitzender des Fachpromotionsausschusses Informatik