Disputation von Robin Khatri am 16.07.2025, 14:00 Uhr
16. Juli 2025, von Reinhard Zierke
Einladung zur hochschulöffentlichen Disputation im Rahmen des Promotionsverfahrens von Robin Khatri
Titel der Dissertation: Computational estimation of cell types, and their dynamics in health and disease
The dissertation presents a novel semi-supervised cell type deconvolution framework with biologically motivated constraints. The method shows robust performance across data modalities. Using cell type deconvolution on multi-omic datasets, the research identified: 1. ustekinumab as a drug targeting pathogenic T cells in antineutrophil cytoplasmic antibody-associated glomerulonephritis, and 2. glioblastoma subgroups that demonstrated better prognostic value than current molecular classifications..
The presentation will be given in English.
Datum und Uhrzeit: Mittwoch, 16. Juli 2025 um 14:00 Uhr
Ort: Zentrum für Bioinformatik, Albert-Einstein-Ring 8-10, Raum 2330
Betreuer: Prof. Dr. Jan Baumbach, Prof. Dr. Stefan Bonn
Prof. Dr. Matthias Rarey
Vorsitzender des Fachpromotionsausschusses Informatik